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1

New COX-2/5-LOX Inhibitors: Apoptosis-Inducing Agents Potentially Useful in Prostate Cancer Chemotherapy

Goossens, Jean-François, Houssin, Raymond, Durant, François, Hénichart, Jean-Pierre, Pommery, Nicole, Taverne, Thierry, Telliez, Aurélie, Goossens, Laurence, Charlier, Caroline, Pommery, Jean

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 325 KB

english, 2004

2

ChemInform Abstract: Nitration of 6-Hydroxy-1-methylpyridin-2-one.

Edith Bouey-Bencteux, Raymond Houssin, Charles Dogimont, Jean-Pierre Henichart

Journal:

Year:

1999

File:

PDF, 26 KB

1999

3

ChemInform Abstract: A New Scaffold for Dipeptide β-Turn Mimetics: Expeditious Synthesis of an Unsaturated 6,5-Fused Bicyclic Lactam.

Regis Millet, Raymond Houssin, Jean-Pierre Henichart, Benoit Rigo

Journal:

Year:

2000

File:

PDF, 35 KB

2000

4

ChemInform Abstract: Synthesis, DNA Binding, Topoisomerases Inhibition, and Cytotoxic Properties of 4-Arylcarboxamidopyrrolo-2-carboxyanilides.

Fabienne Dudouit, Jean-Francois Goossens, Raymond Houssin, Jean-Pierre Henichart, Pierre Colson, Claude Houssier, Nathalie Gelus, Christian Bailly

Journal:

Year:

2000

File:

PDF, 32 KB

2000

5

ChemInform Abstract: A New Synthesis of N-Alkyl Pyrazolidine-3,5-diones and Tetrahydropyridazine-3,6-diones.

Bertrand Le Bourdonnec, Emmanuelle Meulon, Said Yous, Raymond Houssin, Jean-Pierre Henichart

Journal:

Year:

2001

File:

PDF, 30 KB

2001

6

ChemInform Abstract: Conformationally Constrained Dipeptides. Obtention of Enantiomerically Pure 6-Acetamido-5-oxo-1,2,3,5,6,7-hexahydro-3-indolizine Carboxylic Acid.

Regis Millet, Emmanuelle Meulon, Laurence Goossens, Raymond Houssin, Jean-Pierre Henichart, Benoit Rigo

Journal:

Year:

2001

File:

PDF, 35 KB

2001

7

ChemInform Abstract: N-Aminoindoline Derivatives as Inhibitors of 5-Lipoxygenase.

Corinne Audouin, Nathalie Mestdagh, Marie-Agnes Lassoie, Raymond Houssin, Jean-Pierre Henichart

Journal:

Year:

2001

File:

PDF, 27 KB

2001

8

ChemInform Abstract: A Synthesis of New Pyrrolo[3,2-c]quinolines.

Fabienne Dudouit, Raymond Houssin, Jean-Pierre Henichart

Journal:

Year:

2001

File:

PDF, 32 KB

2001

9

An Efficient Synthesis of the New Benzo[c]pyrido[2,3,4-kl]acridine Skeleton.

Sarah Chackal, Raymond Houssin, Jean-Pierre Henichart

Journal:

Year:

2002

File:

PDF, 33 KB

2002

10

Metalation of 4-Oxazolinyloxazole Derivatives. A Convenient Route to 2,4-Bifunctionalized Oxazoles.

Axel Couture, Pierre Grandclaudon, Christophe Hoarau, Josephine Cornet, Jean-Pierre Henichart, Raymond Houssin

Journal:

Year:

2002

File:

PDF, 31 KB

2002

11

ChemInform Abstract: Novel Potent Substance P and Neurokinin A Receptor Antagonists. Conception, Synthesis and Biological Evaluation of Indolizine Derivatives.

Regis Millet, Juozas Domarkas, Benoit Rigo, Laurence Goossens, Jean-Francois Goossens, Raymond Houssin, Jean-Pierre Henichart

Journal:

Year:

2002

File:

PDF, 36 KB

2002

12

Studies on Pyrrolidinones. Synthesis of New α-Pyridones Derivatives.

Natacha Malecki, Raymond Houssin, Jean-Pierre Henichart, Daniel Couturier, Ferdinand Petra, Laurent Legentil, Benoit Rigo

Journal:

Year:

2003

File:

PDF, 165 KB

2003

13

Highly Cytotoxic Benzo[c]pyrido[2,3,4-kl]acridines.

Sarah Chackal, Michael Facompre, Raymond Houssin, Jean-Francois Goossens, Nicole Pommery, Jean-Pierre Henichart, Christian Bailly

Journal:

Year:

2003

File:

PDF, 144 KB

2003

14

New Benzo[5,6]pyrrolizino[1,2-b]quinolines as Cytotoxic Agents.

Aurore Perzyna, Frederique Klupsch, Raymond Houssin, Nicole Pommery, Amelie Lemoine, Jean-Pierre Henichart

Journal:

Year:

2004

File:

PDF, 80 KB

2004

15

A Convenient New Synthesis of 1,2-Diarylpyrroles from 3-Ethoxycarbonyl-4-oxo-4-phenylbutyraldehyde.

Aurelie Delayen, Laurence Goossens, Raymond Houssin, Jean-Pierre Henichart

Journal:

Year:

2005

File:

PDF, 18 KB

2005

16

Electrophilic Nitration of Electron-Rich Acetophenones.

Natacha Malecki, Pascal Carato, Raymond Houssin, Philippe Cotelle, Jean-Pierre Henichart

Journal:

Year:

2006

File:

PDF, 27 KB

2006

17

A short and unequivocal synthesis of 5-aminotetrazolo[1,5-a]-quinazoline as a tricyclic analogue of 4-(3-bromoanilino)-6,7-dimethoxyquinazoline (PD 153035)

Edith Bencteux, Raymond Houssin

Journal:

Journal of Heterocyclic Chemistry

Year:

1997

File:

PDF, 272 KB

1997

18

A new scaffold for dipeptide β-turn mimetics: Expeditious synthesis of an unsaturated 6,5-fused bicyclic lactam

Régis Millet, Raymond Houssin, Jean-Pierre Hénichart, Benoît Rigo

Journal:

Journal of Heterocyclic Chemistry

Year:

1999

File:

PDF, 294 KB

1999

19

A new synthesis of N-alkyl pyrazolidine-3,5-diones and tetrahydropyridazine-3,6-diones

Bertrand Le Bourdonnec, Emmanuelle Meulon, Saïd Yous, Raymond Houssin, Jean-Pierre Hénichart

Journal:

Journal of Heterocyclic Chemistry

Year:

2000

File:

PDF, 335 KB

2000

20

Conformationally constrained dipeptides. Obtention of enantiomerically pure 6-acetamido-5-oxo-1,2,3,5,6,7-hexahydro-3-indolizine carboxylic acid

Régis Millet, Emmanuelle Meulon, Laurence Goossens, Raymond Houssin, Jean-Pierre Hénichart, Benoît Rigo

Journal:

Journal of Heterocyclic Chemistry

Year:

2000

File:

PDF, 276 KB

2000

21

A synthesis of new pyrrolo[3,2-c]quinolines

Fabienne Dudouit, Raymond Houssin, Jean-Pierre Hénichart

Journal:

Journal of Heterocyclic Chemistry

Year:

2001

Language:

english

File:

PDF, 45 KB

english, 2001

22

Studies on pyrrolidinones. Synthesis of new α-pyridones derivatives

Natacha Malecki, Raymond Houssin, Jean-Pierre Héanichart, Daniel Couturier, Ferdinand Petra, Laurent Legentil, Benoîct Rigo

Journal:

Journal of Heterocyclic Chemistry

Year:

2003

Language:

english

File:

PDF, 75 KB

english, 2003

23

Synthesis of 8-substituted tetrahydro-γ-carbolines

Alexandre Bridoux, Laurence Goossens, Raymond Houssin, Jean-Pierre Héanichart

Journal:

Journal of Heterocyclic Chemistry

Year:

2006

Language:

english

File:

PDF, 436 KB

english, 2006

24

Structure—neuromuscular blocking activity relationships of ketophosphonium salts

Raymond Houssin, Jean-Pierre Hénichart, Michel Foulon, François Baert

Journal:

Journal of Pharmaceutical Sciences

Year:

1980

Language:

english

File:

PDF, 441 KB

english, 1980

25

Design, synthesis, DNA binding, and biological activity of a series of DNA minor-groove-binding intercalating drugs

Christian Bailly, Jean-Pierre Henichart, Nicole Pommery, Raymond Houssin

Journal:

Journal of Pharmaceutical Sciences

Year:

1989

Language:

english

File:

PDF, 925 KB

english, 1989

26

Conformational analysis by 13C spin–lattice relaxation times. Evidence for an intramolecular CH … N hydrogen-bond in a 4H-1,2,4-triazole derivative

Raymond Houssin, Jean-Pierre Hénichart

Journal:

Magnetic Resonance in Chemistry

Year:

1981

Language:

english

File:

PDF, 257 KB

english, 1981

27

Molecular interaction between bleomycin and amsacrine in the presence of cupric ions

Jean-Luc Bernier, Abderraouf Kenani, Raymond Houssin, Nicole Helbecque, Michel̀e Lohez, Bernard Hecquet, Jean-Pierre Hénichart

Journal:

Journal of Inorganic Biochemistry

Year:

1986

Language:

english

File:

PDF, 966 KB

english, 1986

28

Complexation of copper(II) by a peptide hybrid of bleomycin and amsacrine. Circular dichroism and electron spin resonance studies

Christian Bailly, Jean-Pierre Catteau, Nicole Helbecque, Jean-Luc Bernier, Raymond Houssin, Claude Denis, Jean-Pierre Hénichart

Journal:

Journal of Inorganic Biochemistry

Year:

1987

Language:

english

File:

PDF, 521 KB

english, 1987

29

Metal-complexing, DNA-binding and DNA-cleaving properties of a synthetic molecule AMBIGLU, a simplified model for the study of bleomycin

Abderraouf Kenani, Christian Bailly, Nicole Helbecque, Raymond Houssin, Jean-Luc Bernier, Jean-Pierre Henichart

Journal:

European Journal of Medicinal Chemistry

Year:

1989

Language:

english

File:

PDF, 915 KB

english, 1989

30

Synthesis of condensed quinolines and quinazolines as DNA ligands

Natacha Malecki, Pascal Carato, Benoı̂t Rigo, Jean-François Goossens, Raymond Houssin, Christian Bailly, Jean-Pierre Hénichart

Journal:

Bioorganic & Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 272 KB

english, 2004

31

New benzo[5,6]pyrrolizino[1,2-b]quinolines as cytotoxic agents

Aurore Perzyna, Frédérique Klupsch, Raymond Houssin, Nicole Pommery, Amélie Lemoine, Jean-Pierre Hénichart

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 253 KB

english, 2004

32

Design, synthesis and biological evaluation of substituted dioxodibenzothiazepines and dibenzocycloheptanes as farnesyltransferase inhibitors

Pauline Gilleron, Nicolas Wlodarczyk, Raymond Houssin, Amaury Farce, Guillaume Laconde, Jean-François Goossens, Amélie Lemoine, Nicole Pommery, Jean-Pierre Hénichart, Régis Millet

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 398 KB

english, 2007

33

2,6-Diphenylthiazolo[3,2-b][1,2,4]triazoles as telomeric G-quadruplex stabilizers

Jamal El Bakali, Frédérique Klupsch, Aurore Guédin, Bertrand Brassart, Gaëlle Fontaine, Amaury Farce, Pascal Roussel, Raymond Houssin, Jean-Luc Bernier, Philippe Chavatte, Jean-Louis Mergny, Jean-Fran

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 387 KB

english, 2009

34

Synthesis and biological evaluation of a new family of anti-benzylanilinosulfonamides as CA IX inhibitors

Anne Thiry, Aurélie Delayen, Laurence Goossens, Raymond Houssin, Marie Ledecq, Aurélie Frankart, Jean-Michel Dogné, Johan Wouters, Claudiu T. Supuran, Jean-Pierre Hénichart, Bernard Masereel

Journal:

European Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 486 KB

english, 2009

35

Synthesis of 1,4-diazepin-5-ones under microwave irradiation and their reduction products

Nicolas Wlodarczyk, Pauline Gilleron, Régis Millet, Raymond Houssin, Jean-Pierre Hénichart

Journal:

Tetrahedron Letters

Year:

2007

Language:

english

File:

PDF, 136 KB

english, 2007

36

Depsipeptide analogs of the antitumor drug distamycin containing thiazole amino acids residues

Christian Bailly, Raymond Houssin, Jean-Luc Bernier, Jean-Pierre Henichart

Journal:

Year:

1988

Language:

english

File:

PDF, 815 KB

english, 1988

37

Analog of dolastatin 3 synthesis, 1h nmr studies and spatial conformation

Jean-Luc Bernier, Raymond Houssin, Jean-Pierre Henichart

Journal:

Year:

1986

Language:

english

File:

PDF, 531 KB

english, 1986

38

Synthesis of an azabicycloalkane amino acid scaffold as potential rigid dipeptide mimetic

Régis Millet, Juozas Domarkas, Pauline Rombaux, Benoı̂t Rigo, Raymond Houssin, Jean-Pierre Hénichart

Journal:

Tetrahedron Letters

Year:

2002

Language:

english

File:

PDF, 67 KB

english, 2002

39

Synthesis, DNA binding, topoisomerases inhibition and cytotoxic properties of 4-arylcarboxamidopyrrolo-2-carboxyanilides

Fabienne Dudouit, Jean-François Goossens, Raymond Houssin, Jean-Pierre Hénichart, Pierre Colson, Claude Houssier, Nathalie Gelus, Christian Bailly

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2000

Language:

english

File:

PDF, 326 KB

english, 2000

40

N-Aminoindoline derivatives as inhibitors of 5-lipoxygenase

Corinne Audouin, Nathalie Mestdagh, Marie-Agnès Lassoie, Raymond Houssin, Jean-Pierre Hénichart

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 166 KB

english, 2001

41

Synthesis and Activity of a New Methoxytetrahydropyran Derivative as Dual Cyclooxygenase-2/5-Lipoxygenase Inhibitor

Sabine Barbey, Laurence Goossens, Thierry Taverne, Joséphine Cornet, Valérie Choesmel, Céline Rouaud, Gilles Gimeno, Sylvie Yannic-Arnoult, Catherine Michaux, Caroline Charlier, Raymond Houssin, Jean-

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 160 KB

english, 2002

42

Highly cytotoxic benzo[c]pyrido[2,3,4-kl]acridines

Sarah Chackal, Michael Facompré, Raymond Houssin, Jean-François Goossens, Nicole Pommery, Jean-Pierre Hénichart, Christian Bailly

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 180 KB

english, 2003

43

Synthesis and cytotoxicity of analogues of the antibiotic BE 10988 inhibitors of DNA topoisomerase II

Marc-Olivier Catrycke, Raymond Houssin, Jean-Pierre Hénichart, Bruno Pfeiffer, Pierre Renard, Laurent Dassonneville, Christian Bailly

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 336 KB

english, 1999

44

Novel potent substance P and neurokinin A receptor antagonists. Conception, synthesis and biological evaluation of indolizine derivatives

Régis Millet, Juozas Domarkas, Benoı̂t Rigo, Laurence Goossens, Jean-François Goossens, Raymond Houssin, Jean-Pierre Hénichart

Journal:

Bioorganic & Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 181 KB

english, 2002

45

Conformation of the tripeptide Cbz-Pro-Leu-Trp-OBzl(CF3)2 deduced from two-dimensional 1H-NMR and conformational energy calculations is related to its affinity for NK1-receptor

Régis Millet, Laurence Goossens, Jean-François Goossens, Philippe Chavatte, Karine Bertrand-Caumont, Raymond Houssin, Jean-Pierre Hénichart

Journal:

Journal of Peptide Science

Year:

2001

Language:

english

File:

PDF, 895 KB

english, 2001

46

Synthesis of a novel conformationally restricted Val-Phe dipeptidomimetic

Pauline Gilleron, Régis Millet, Juozas Domarkas, Amaury Farce, Raymond Houssin, Jean-Pierre Hénichart

Journal:

Journal of Peptide Science

Year:

2006

Language:

english

File:

PDF, 149 KB

english, 2006

47

Bioactive conformations of peptides and mimetics as milestones in drug design: Investigation of NK1receptor antagonists

Solo Goldstein, Michel Neuwels, Florence Moureau, Didier Berckmans, Marie-Agnès Lassoie, Edmond Differding, Raymond Houssin, Jean-Pierre Hénichart

Journal:

International Journal of Peptide Research and Therapeutics

Year:

1995

Language:

english

File:

PDF, 588 KB

english, 1995

48

Synthesis and biological evaluation of tripeptide derivatives of Cbz-Gly-Leu-Trp-OBzl(CF3)2as NK1/NK2ligands

Régis Millet, Jean-François Goossens, Karine Bertrand-Caumont, Raymond Houssin, Jean-Pierre Hénichart

Journal:

International Journal of Peptide Research and Therapeutics

Year:

1999

Language:

english

File:

PDF, 565 KB

english, 1999

49

Synthesis and biological evaluation of conformationally restricted derivatives of tryptophan as NK1/NK2ligands

Régis Millet, Jean-François Goossens, Karine Bertrand-Caumont, Philippe Chavatte, Raymond Houssin, Jean-Pierre Hénichart

Journal:

International Journal of Peptide Research and Therapeutics

Year:

1999

Language:

english

File:

PDF, 1.91 MB

english, 1999

50

Electrophilic Nitration of Electron-Rich Acetophenones

Natacha Malecki, Pascal Carato, Raymond Houssin, Philippe Cotelle, Jean-Pierre Hénichart

Journal:

Monatshefte für Chemie - Chemical Monthly

Year:

2005

Language:

english

File:

PDF, 105 KB

english, 2005